Characteristic of LN metastasis in intrahepatic cholangiocarcinoma
Kanchanin Bunsupha
ABSTRACT
Background: Lymph node metastasis is an important prognostic factor in IHCC. The accuracy of preoperative imaging assessment of LN metastasis is unsatisfactory for detecting metastatic LNs. Therefore, lymph nodes sampling for IHCC without preoperative LN enlargement should be done for accurate LN status assessment. However the extent of LN dissection is still controversial. To address this clinical problem, we need to better understand patterns of the lymphatic outflow.
Objective: To study characteristic of lymphatic metastasis in intrahepatic cholangiocarcinoma and identify the sentinel lymph node
Methods: A prospective study collecting data about LN metastasis in patients who had intrahepatic cholangiocarcinoma in SNK hospital KKU between December 2015 to December 2017 who underwent explore laparotomy surgery
Results: Positive LN12 xx% , Positive LN8 xx% , Positive LN13 xx% , not found the pattern that LN8 and/or LN13 = positive while negative LN12
Conclusions: Lymph nodes in the hepatoduodenal ligament (LN12) may be sentinel nodes for intrahepatic cholangiocarcinoma , negative intraoperative frozen section of LN12 may suggest that no further lymphadenectomy is needed
Key words: Intrahepatic cholangiocarcinoma , Lymph node metastasis , Extended lymphadenectomy